When it comes to the treatment of tinnitus, there seem to be no easy answers, nor uniform practices. Recent research designed to produce tinnitus medication has focused on the relationship between the brain's nerve cells and neurotransmitters such as glutamate. This focus is the result of the discovery that tinnitus sometimes occurs when excessive amounts of glutamate are released by damaged hair cells. One of the leading causes of damage to hair cells and their subsequent emission of excess glutamate is exposure to very loud noise or ototoxic medications.
Despite the fact that glutamate is a naturally occurring neurotransmitter, an overabundance of the substance in the body creates a dangerous imbalance that can cause improper functioning in the brain. There are two ways to realign the neurotransmitter imbalance. The first is through the use of anti-seizure medications like Neurontin to activate GABA receptors that will stop the nonstop neurotransmitter activity caused by the excess amounts of glutamate.
Medicines used for the treatment of anxiety can serve the same purpose. Xanax and Valium are just two examples of drugs that have shown some success when used as tinnitus medication, and which many doctors prescribe for patients suffering from tinnitus. Sometimes these drugs are used in conjunction with anti-seizure medicines, and the combination has proven effective in lowering both the level of sound and the patient's anxiety. However, there is a drawback to using this combination as a tinnitus medication, given that the drugs can create an addiction over time.
The second way to counter the imbalance is through the use of drugs that are naturally hostile to glutamate. These glutamate antagonists have been proven to assist in providing protection for the brain, but have also shown some signs of acting as a hallucinogen. Because of that, researchers have attempted to combine these antagonists with other drugs such as barbiturates to limit any potential adverse neurological effects.
One of the drugs currently being used as tinnitus medication includes Memantine, an oral medication that has been used for some time in the treatment of Alzheimer's disease. A recent study using this drug for tinnitus demonstrated its effectiveness in suppressing glutamate, when it was applied by way of a catheter that is inserted through the ear drum. This delivery method is called transtympanic perfusion, and has demonstrated a consistent ability to bypass the systemic side effects caused by more traditional delivery methods.
There are also a number of experimental medications currently under development or undergoing varying stages of the clinical approval process. These include drugs like Caroverine, another glutamate antagonist, which has been a staple of tinnitus medication in Austria but which has not yet gained approval for use in the United States, as well as the experimental AM-101 which has already been reported to dampen tinnitus effects in test animals.
Lastly a product known as "Tinnitus Miracle" which uses a holistic natural approach to eradicate the underlying causes of tinnitus has proven to be extremely effective in thousands of cases worldwide. Tinnitus Miracle is a treatment guide that can be started immediately and positive effects of the treatment can sometimes be seen in just a few days after starting treatment.
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